β-Catenin Mutations Are Frequent in Calcifying Odontogenic Cysts, but Rare in Ameloblastomas
نویسندگان
چکیده
منابع مشابه
Caveolin-1 expression in odontogenic cysts and ameloblastomas.
OBJECTIVE The aim of this study is to evaluate the caveolin-1 expression in a group of odontogenic cysts and tumors. MATERIAL AND METHOD In this cross-sectional study, the expression of caveolin-1 was evaluated immunohistochemically in 75 samples including 18 cases of dentigerous cyst, 18 odontogenic keratocysts, 3 orthokeratinized odontogenic cysts, 2 calcifying odontogenic cysts and 34 amel...
متن کاملMicrovessel density in follicular cysts, keratocystic odontogenic tumours and ameloblastomas.
PURPOSE Multicystic ameloblastoma is a benign epithelial odontogenic tumor that exhibits a more aggressive behavior than follicular cyst and keratocystic odontogenic tumor (KCOT). The aim of this study was to perform an immunohistochemical evaluation of the mean microvessel density (MVD) effect on clinical behavior of odontogenic lesions and to determine whether peritumoral or intratumoral MVD ...
متن کاملImmunoexpression of Wnt/β-catenin signaling pathway proteins in ameloblastoma and calcifying cystic odontogenic tumor
BACKGROUND Wnt/β-catenin signaling pathway is essential for the beginning of odontogenesis and may be involved in the development and progression of some odontogenic tumors. Thus, the aim of this study was to comparatively evaluate the immunohistochemical expression of Wnt/β-catenin signaling pathway proteins in a series of AME and CCOT. MATERIAL AND METHODS Immunohistochemical reactions were...
متن کاملExpression of β-catenin and AXIN2 in ameloblastomas
AIM OF THE STUDY To investigate the expression status and association of β-catenin and AXIN2 in ameloblastoma. MATERIAL AND METHODS 30 ameloblastoma specimens and 10 normal oral mucosa tissues were enrolled in the study. The protein and RNA levels of β-catenin and AXIN2 were detected by immunohistochemistry staining, Western blot, and real-time PCR analysis. The relationship between β-catenin...
متن کاملRecurrent Peripheral Calcifying Cystic Odontogenic Tumor (Calcifying Odontogenic Cyst)
Peripheral calcifying cystic odontogenic tumor (PCCOT) is a rare odontogenic lesion, which represents about 1% of jaw cysts. Here we report clinicopathologic, radiographic and CT scan images of a new case of recurrent large PCCOT located in mandibular gingiva in a 77-year-old male with history of a nodular mass in the same area, which had been completely excised 3 years ago. In reviewing the...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2003
ISSN: 0002-9440
DOI: 10.1016/s0002-9440(10)63528-6